Alka-Seltzer was first invented in 1931 and still works just as well as it did back in the day. Alka-Seltzer was first sold by Dr. Miles Medicine Company and became an essential pain reliever that almost every American used. Alka-Seltzer stayed under American ownership for quite some time until Bayer eventually bought it in 1978.
Bayer is a German-based company that is known for buying up several different types of medicines and has been called out for trying to create a monopoly which they have denied. Sadly, most of the companies around are owned by monopolies, so who knows what will happen in the future.